Workpackages

The project plan of the MedVet-Staph project comprises three workpackages (WP) with eleven individual projects (IP) and two cross-sectional activities (CSA).

Please click on the IP of interest to get further information!

Workpackage 1: Epidemiology of human LA-MRSA
infection and colonization

IP 3 LA-MRSA adaption properties and spread from food to consumers

Principal investigators:
Dr. med. vet. Alexandra Fetsch, PD Dr. med. vet. Bernd-Alois Tenhagen
Federal Institute for Risk Assessment (BfR)

IP 4 Human bacteraemic and nosocomial infections by MRSA CC398

Principal investigators:
Dr. med. Robin Köck, PD Dr. med. Alexander Mellmann
Institut für Hygiene, Universitätsklinikum Münster

IP 8 Combating zoonotic MRSA from mecA to mecC: Applied hygiene concepts and data analysis of a multilevel characterization approach in veterinary medicine

Principal investigators:
Dr. med. vet. Birgit Walther
Free University of Berlin, Institute of Microbiology and Epizootics (IMT-B)

IP 9 Studies on acquisition of MRSA of primarily animal origin (in particular livestock) by humans, adaptation to humans and human-to-human transmission

Principal investigators:
Prof. Dr. Wolfgang Witte, Dr. med. vet. Christiane Cuny, (laboratory part)
PD Dr. med. Tim Eckmanns (epidemiological part), Robert Koch Institute (RKI)

Workpackage 2: Strategies for intervention, therapy
and diagnosis of LA-MRSA

IP 1 Adaptation of livestock-associated S. aureus strains with zoonotic capability to the human host and the health care environment

Principal investigators:
Prof. Dr. med. Karsten Becker
University Hospital Münster, Institute of Medical Microbiology (IMM-MS)

IP 5 Studies and development of models for pig-to-pig and pig-to-human spread of MRSA on farms

Principal investigators:
Prof. Dr. Ing. agr. Thomas Selhorst
Friedrich-Loeffler-Institut, Institute of Epidemiology (FLI-WU)

IP 10 Clinical effectiveness of decolonization therapies among patients carrying livestock-associated MRSA

Principal investigators:
PD Dr. med. Tobias Goerge
University Hospital Münster, Clinic and Policlinic for Dermatology (DERM-MS)

IP 11 Development of diagnostic test kits for rapid multianalyte diagnosis of resistance determinants and molecular characteristics of zoonotic S. aureus

Principal investigators:
Dr. Boris Oberheitmann
Q-Bioanalytic GmbH (QBio-B)

Workpackage 3: Influences of ecological niches
and host-adaptation on LA-MRSA

IP 2 Transcriptional profiling of CC398 isolates obtained from human and animal

Principal investigators:
PD Dr. sc. nat. ETH Markus Bischoff
University of Saarland, Institute of Med. Microbiology & Hygiene (IMH-HO)

IP 7 Influence of antibiotic resistant staphylococcal species on persistence and dissemination of LA-MRSA

Principal investigators:
PD Dr. med. Wilma Ziebuhr
University of Würzburg, Institute for Molecular Infection Biology (MIB-WÜ)

IP 6 Novel resistance genes of MRSA/MSSA and factors that influence their dissemination

Principal investigators:
Prof. Dr. med. vet. Stefan Schwarz
Friedrich-Loeffler-Institut, Institute of Farm Animal Genetics (FLI-NM)

Workpackage CSA1* und CSA2

CSA 2* Data Warehouse, Geographic Information and Early Warning System for Zoonotic S. aureus/MRSA

Principal investigators:
Univ.-Prof. Dr. med. Dag Harmsen
University Hospital Münster, Department of Periodontology (INF-MS)

* first project period (2010-2013) only

CSA 2 Promotion of young scientists & coordination of the consortium

Principal investigators:
Dr. med. Robin Köck
University Hospital Münster, Institute of Hygiene (IFH-MS)

 

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